Category Archives: Health Innovations

Celegene making progress in Treatment for Ulcerative Colitis

Celegene is making progress in its treatment for Ulcerative Colitis by its drug Ozanimod, which is under Phase 2 Clinical Trials currently.

About Ulcerative Colitis: Ulcerative colitis is a chronic, relapsing condition triggered by an abnormal, prolonged immune response that creates long-lasting inflammation and ulcers (sores) in the mucosa (lining) of the large intestine (colon). Symptoms usually develop over time, rather than suddenly. The disease can be debilitating and can sometimes lead to life-threatening complications. Ulcerative colitis is the most common form of inflammatory bowel disease worldwide. About one in every 198 people in Europe, and one in every 402 people in North America, have ulcerative colitis. In 2004, 2.1 million prescriptions were written to treat ulcerative colitis, and 716,000 ambulatory care visits were related to the disease. In 2010, there were 107,000 hospitalizations due to ulcerative colitis.

Following is a press release by the company dated 18 march 2016. Continue reading

Benefits of Natural Omega 3 Supplements

Learn How Omega 3 Fatty Acids Can Improve Your Overall Health. The demands of modern lifestyle are placing high stress on most human bodies living in urban conditions. It is hard to keep up with what all is going on these days in the fields of health, but once thing we can know for sure is that better health is a goal that is most certainly worth achieving.

If our body is taking care of us instead of us constantly having to seek repairs for our body, then we are living the human experience the way that it was meant to be lived. There are a lot of benefits to taking Omega 3 fatty acid as often as we can get it, because science has proven that this essential ingredient in fish oil does our bodies and minds a huge amount of good. Continue reading

Antioxidant Levels Key to Prostate Cancer Risk in Some Men

Greater levels of selenium, vitamin E and the tomato carotenoid lycopene have been shown to reduce prostate cancer in one out of every four Caucasian males, or those who inherit a specific genetic variation that is particularly sensitive to oxidative stress, say US researchers.

Conversely, if carriers of this genetic variant have low levels of these vitamins and minerals, their risk of aggressive prostate increases substantially, as great as 10-fold, over those who maintain higher levels of these nutrients, they write in today’s issue of Cancer Research.

“This large prospective study provides further evidence that oxidative stress may be one of the important mechanisms for prostate cancer development and progression, and adequate intake of antioxidants, such as selenium, lycopene and vitamin E, may help prevent prostate cancer,” said Dr Haojie Li, a researcher at the Brigham and Women’s Hospital and Harvard Medical School.

The new findings are based on an analysis of 567 men diagnosed with prostate cancer between 1982 and 1995, and 764 cancer-free men from the Physicians Health Study.

The initial goal of this study was to assess the effect of aspirin and beta-carotene on men’s health. Li’s team decided to check for variants of the gene that codes for manganese superoxide dismutatase (MnSOD), an important enzyme that works as an antioxidant in human cells to defend against disease.

The MnSOD gene is passed from parents to offspring in one of three forms: VV, VA or AA.

“Compared with men with the MnSOD VV or VA genotype, people with the AA genotype seem to be more sensitive to the antioxidant status,” said Li. “Men with the AA genotype are more susceptible to prostate cancer if their antioxidant levels are low.”

  • The study’s results found that a quarter of the men in the study carried the MnSOD AA genotype, half carried the VA genotype, and the remaining quarter carried the VV genotype.
  • The results indicated that the VA and VV men were at equivalent risk for developing prostate cancer across all levels of antioxidants in their blood.
  • But compared to MnSOD VV or VA carriers in the lowest quartile of selenium levels, MnSOD AA males had an 89 per cent greater risk for developing aggressive prostate cancer if they had low blood levels of the mineral.
  • On the other hand, MnSOD AA carriers with high selenium – those men in the highest quartile – had a 65 per cent lower risk than the MnSOD VV or VA males who maintained low levels of selenium.

“The levels of selenium in the highest quartile of these men are not abnormally high,” Li said. “Our range is neither extremely high nor extremely low.”

While similar trends were observed for lycopene and vitamin E when te

sted independently, the contrast in relative risk was most pronounced for the men who had high blood levels for all three antioxidants combined, said the researchers.

“Among men with the MnSOD AA genotype, we observed a 10-fold difference in risk for aggressive prostate cancer, when comparing men with high versus low levels of antioxidants combined,”said Li. “In contrast, among men with the VV or VA genotype, the prostate cancer risk was only weakly altered by these antioxidant levels.”

“Our study, as well as many other epidemiological studies, encourages dietary intake of nutrients such as lycopene from tomato products, or supplements for vitamin E and selenium to reduce risk of prostate cancer,” said Li.

Prostate cancer is one of the biggest cancer killers in industrial countries and affects more than 500,000 men worldwide every year. This number is expected to increase with the aging population.

Similar interactions between dietary antioxidants and the variations in the MnSOD gene have previously been linked to risk for breast cancer.

For more information visit: http://www.prostacet.com

Stem Cell Banking Information For Pregnant Women

Stem cell banking is a trend that is catching up in different parts of the world. Stem cells from umbilical cord blood are collected at the time of delivery when the cord connecting the baby to mother is cut.

Stem cell therapy has the potential to radically change the treatment of human disease. Cord blood technology has been used in the US since 1990. Parents and guardians are increasingly seeking to store their children’s stem cells as an insurance policy against future life-threatening diseases.

Stem cells have the potential to grow into any other type of cells. They are the building blocks of the blood and immune system that can reproduce into other cell types, including heart, muscle and nerve. Within a few weeks, 300 people have approached us for information on stem cell banking.

Umbilical cord blood stem cells have been used over the years in an increasing number of treatments including leukemia, malignant tumors, blood disorders, red cell disorders and more.

Currently research in the use of stem cells to treat more than 85 diseases is being undertaken. Stem cells are the natural repair kit of the human body. In the last few years, more than 10,000 patients in over 150 countries have been treated with cord blood stem cell transplants.

Europe’s largest stem cell banking company, Cryo-Save, also launched operations in India recently. The company sees huge potential in this business and has has invested in 10 stem cell storage banks. The company is offering a stem cell storage kit at Rs.75,000 (about USD 1500) that includes the cost of collecting stem cells at the time of delivery to processing and preserving it for next 21 years. The company has also tied up with several hospitals and gynecologists to make expecting mothers aware about the benefits of stem cell therapy.

We believe similar companies operate in US also, though the costs maybe higher. While it is hard to plan much ahead in life, it looks like there are couple who are ready to spend and buy this “stem cell banking” insurance for their kids future health. As always, please ask questions before opting for any service, and insist of clear answers in layman’s terms, and get all agreements in writing.

Does Alli Weight-Loss Pill Work?

Alli weight-loss pill: Does it work? Is Alli the solution to your weight-loss woes?

Alli (pronounced AL-eye) is meant for overweight adults who are struggling to shed excess pounds. Alli is the only FDA approved, over-the-counter weight loss product. It works and its safe — that’s why it has got FDA approval for weight loss. It works by preventing your body from absorbing some of the fat you eat.

alli-weight-loss-pill-drug-program-fda-review

Following is a detailed Q&Ato obtain Alli Weight Loss Drug Review: A Mayo Clinic specialist discusses the effectiveness of Alli, an over-the-counter weight-loss pill. Another drug is available to aid your weight-loss efforts, but this time you don’t need a prescription.

With its easy access and weight-loss promises, is Alli the best answer for weight-loss so far?

Donald Hensrud, M.D., a preventive medicine and nutrition specialist at Mayo Clinic, Rochester, Minn., answers common questions about Alli.

What is Alli?
Alli is the reduced-strength version of orlistat (Xenical), a prescription drug to treat obesity. It’s approved for over-the-counter sale to overweight adults 18 years and older. Alli is meant to be used in conjunction with a low-calorie, low-fat diet and regular exercise.

How does Alli work?
Alli promotes weight loss by decreasing absorption of fat by the intestines, which reduces the number of calories you absorb. Lipase, an enzyme found in the digestive tract, helps break down dietary fat into smaller components, so it can be used or stored for energy.

Alli works by disabling lipase, which prevents the enzyme from breaking down the fat while it’s in your digestive tract. The undigested fat continues through the intestines and is eliminated through bowel movements.Alli is taken with fat-containing meals, up to three times a day.

Because of how Alli works, it’s recommended that you eat no more than 15 grams of fat with each meal. Eating higher amounts of fat can cause unwanted effects, such as urgent bowel movements, diarrhea and gas with oily spotting. For more information click here.

How much weight could I lose using Alli?

Alli can help you lose weight, but the weight loss likely won’t be great — perhaps just a few pounds more than you would lose with diet and exercise alone.

Only a small number of studies have evaluated the effectiveness of Alli. And many of the weight-loss estimates are based on studies conducted on its prescription-strength counterpart, Xenical.The average weight loss for prescription-strength Xenical is modest — about 6 pounds greater than diet and exercise alone after one year.

So at half the strength, Alli could conceivably result in an average of 3 pounds lost in a year in addition to the approximately 8 pounds you could expect to lose from diet and exercise alone.

When shouldn’t I take Alli?

You shouldn’t take Alli if you:
– Are at a healthy weight
– Are taking cyclosporine Have had an organ transplant
– Have problems absorbing food
– The drug also may pose risks for anyone who takes blood-thinning medication or has diabetes or thyroid disease.

Orlistat decreases the absorption of certain fat-soluble vitamins — for example, vitamins A, D and E. So if you’re taking Alli, you need to take a daily vitamin supplement (at a time different from when you take Alli) to prevent potential nutrient deficiencies. For more information click here.

How long do I need to take Alli?

According to the manufacturer, most weight loss occurs within the first six months. Many people who take medications to lose weight regain the weight they lost when they stop taking the medication. Therefore, to keep the weight off, many people continue taking medications indefinitely along with eating a low-calorie diet and exercising regularly.

How does Alli fit into a healthy weight-loss plan?

As you consider Alli as a weight-loss aid, make sure that you make every effort to exercise, change your eating habits and adjust any other lifestyle factors that have contributed to your excess weight. Alli isn’t the easy answer to weight loss and is meant only to supplement — not replace — a healthy diet and regular exercise. Now, you can create the most effective weight-loss plan for you. For more information click here.